1. McGraw CE, Peng D, Sandoval NR. Synthetic biology approaches: the next tools for improved protein production from CHO cells. Current Opinion in Chemical Engineering. 2020; 30, 26-33. 10.1016/j.coche.2020.06.003

  2. Kim NM, Sinnott RW, Sandoval NR. Transcription factor-based biosensors and inducible systems in non-model bacteria: current progress and future directions. Current opinion in biotechnology. 2020; 64, 39-46. 10.1016/j.copbio.2019.09.009

  3. Joseph RC, Kim NK, Sandoval NR. Recent developments in the synthetic biology tool kit in Clostridium. Frontiers in Microbiology. 2018; 9, 154. 10.3389/fmicb.2018.00154

  4. Rohlhill J, Sandoval NR, Papoutsakis ET. Sort-seq approach to engineering a formaldehyde-inducible promoter for dynamically regulated Escherichia coli growth on methanol. ACS Synthetic Biology. 2017; 6 (8), pp 1584–1595. 10.1021/acssynbio.7b00114

  5. Long CP, Au J, Sandoval NR, Gebreselassie NA, Antoniewicz MR. Enzyme I facilitates reverse flux from pyruvate to phosphoenolpyruvate in Escherichia coli. Nature Communications. 2017; 8:14316. doi: 10.1038/ncomms14316

  6. Sandoval NR, Papoutsakis ET: Engineering membrane and cell-wall programs for tolerance to toxic chemicals: Beyond solo genes. Curr Opin Microbiol 2016, 33:56-66. 10.1016/j.mib.2016.06.005

  7. CP Long, JE Gonzalez, NR Sandoval, MR Antoniewicz: Characterization of physiological responses to 22 gene knockouts in Escherichia coli central carbon metabolism, Metab eng, 37 (2016). 10.1016/j.ymben.2016.05.006

  8. Cordova LT, Lu J, Cipolla RM, Sandoval NR, and Antoniewicz MR: Simultaneous utilization of glucose and xylose by an evolved Thermus thermophilus strain elucidated by 13C metabolic flux analysis and genome sequencing. Metab eng, 37 (2016) 63-71. 10.1016/j.ymben.2016.05.001

  9. Sandoval NR, Venkataramanan KP, Groth TS, Papoutsakis ET: Genome sequencing identifies Spo0A inactivation in Clostridium pasteurianum as imparting enhanced tolerance to crude glycerol and increased growth-associated butanol production. Biotechnology for biofuels, 8 (2015) 227. 10.1186/s13068-015-0408-7

  10. Gaida SM*, Sandoval NR*, Nicolaou SA, Chen Y, and Papoutsakis ET: Expression of heterologous sigma factors enables functional screening of metagenomic and heterologous genomic libraries Nat Comm 2015, 6:7045. 10.1038/ncomms8045 (*Equal contribution) 

  11. Whitaker WB, Sandoval NR, Bennett RK, and Papoutsakis ET: Synthetic methylotrophy: engineering the production of biofuels and chemicals based on the biology of aerobic methanol utilization. Curr Opin Biotechnol. (2015) 33:165–175. 10.1016/j.copbio.2015.01.007

  12. Glebes TY, Sandoval NR, Gillis JH and Gill RT: Comparison of genome-wide selection strategies to identify furfural tolerance genes in Escherichia coli. Biotechnol Bioeng. (2015) 112:129-140. 10.1002/bit.25325

  13. Glebes TY, Sandoval NR, Reeder PJ, Schilling KD, Zhang M, Gill RT: Genome-wide mapping of furfural tolerance genes in Escherichia coli. PLoS One 9(1): e87540. 10.1371/journal.pone.0087540

  14. Sandoval NR, Kim JYH, Reeder P, Glebes TY, Aucoin HR, Warner JR, and Gill RT:  A Strategy for Directing Combinatorial Genome Engineering in E. coli. PNAS 26 (2012) 10540-10545. 10.1073/pnas.1206299109

  15. Sandoval NR, Mills TY, Zhang M, and Gill RT: Elucidating acetate tolerance in E. coli using a genome-wide approach. Metab Eng. 13 (2010) 214-224. 10.1016/j.ymben.2010.12.001

  16. Mills TY*, Sandoval NR*, and Gill RT: Cellulosic hydrolysate toxicity and tolerance mechanisms in Escherichia coli. Biotechnol Biofuels (2009) 2:26. 10.1186/1754-6834-2-26 (*Equal contribution)

  17. Gall S, Lynch MD, Sandoval NR, and Gill RT: Parallel mapping of genotypes to phenotypes contributing to overall biological fitness. Metab Eng. 10 (2008) 382-393. 10.1016/j.ymben.2008.08.003

  18. Warnecke TE, Lynch MD, Karimpour-Fard A, Sandoval NR, and Gill RT: A genomics approach to improve the analysis and design of strain selections. Metab Eng 10 (2008) 154-165. 10.1016/j.ymben.2008.04.004

"Scientific progress is the discovery of a more and more comprehensive simplicity."

- Georges Lemaître -

Department of Chemical and Biomolecular Engineering | School of Science and Engineering | Tulane University

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